Skin inflammation after sunburn could promote cancer cell migration

For those who use mometasone to relieve inflammatory skin conditions, it is essential to remember that too much sun can prove deadly.

For those who use mometasone to relieve inflammatory skin conditions, it is essential to remember that too much sun can prove deadly. While various types of dermis irritation can provoke a wide variety of symptoms, such as rash formation, severe itching or possible infection, side effects of skin inflammation that stem from UV radiation can produce considerably graver conditions in the body.

Researchers from the University of Bonn in Germany have analyzed the potential correlation between UV irradiation prompting skin inflammation to spread cancer cells in blood vessels. Using experimental models with mice, professors tested the effects of inflammatory responses after UV exposure to the skin. After repeated exams with the animals. The researchers discovered that severe sunburns had the capacity to form metastases, or the spreading of cancer from one organ to another, by altering pigment cells within the dermis.  

Dr. Thomas Tuting, a professor at the University of Bonn and leader of the study, was adamant in regards to the severity too much UV exposure could entail.

"The inflammatory reaction of the skin after severe sun exposure promotes the early migration of melanoma cells along vessels within the body," Tuting said in a statement. "Our findings may explain why patients with superficially ulcerated melanomas and neutrophil infiltration frequently develop organ metastases."

Neutrophils are the most abundant type of white blood cells found in mammals, and Tuting and his team found that they played a vital part in migrating the cancer through the body. During the inflammatory process of a serious sunburn, the neutrophils send off alarm signals provoked by UV-damaged keratinocytes in the epidermis. This prompts the cancer ridden cells to leave the burn area and disperse throughout the rest of the body.

Executing proper skin care
The researchers fear that this form of metastasis could expand rapidly in the next few years, which is why protecting yourself from sun damage is crucial. Skin cancer is the most common form of the disease, and UV radiation is a primary reason why. With 3.5 million people currently plagued with skin cancer in the U.S., it is always important to remember to shield your body with sunscreen, even when you think it is unnecessary. 

Mometasone is an ointment that can help aid your skin through inflammatory symptoms brought on by sunburn. You can always buy mometasone from a Canadian online pharmacy if you are in need of urgent skin care.